The Eye Basic Sciences in Practice

The Eye: Basic Sciences in Practice provides highly accessible, one-stop coverage of all the essential basic science required by today’s ophthalmologists and optometrists in training. It is also core reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area.

Building on previous success, this fifth edition has been fully revised in line with current curricula, key research developments and clinical best practice. It succinctly incorporates critical developments in fast-moving fields related to the eye and vision, including genetics, pharmacology, microbiology, immunology, pathology, neurophysiology, neuroanatomy and imaging. Topical coverage includes:

• Major advances in the search for new genes underpinning disease in ophthalmology
• The emergence of new infections such as Ebola, Zika and COVID-19
• The importance of the gastrointestinal tract as an immune organ and its functional dependence on the microbiome
• Key aspects of melanopsin, melatonin and new ways of light sensing

Also, (print purchasers) benefit from access to the complete, fully searchable electronic text, with integrated video and other bonus materials to further explain and expand on key concepts. This combines to make The Eye a more flexible, comprehensive and engaging learning package than ever before.

New to this edition

• A thorough overview of the contents of the book is planned in all key areas of developing knowledge and practice, both in the text in the printed book and that additional information which is provided in the accompanying ebook and online versions.
• A revision of the design of the printed book will enhance its appearance with a clearer range of headings and other text features.
• Anatomy chapter: an expansion of the details on ocular and orbital anatomy; new images of the dural venous system and cerebral circulation; and new information on dural lymphatics.
• Embryology chapter: new material on melanocyte development in choroid.
• Genetics chapter: a full update of the clinical and northern blotting sections; in genomics an overview of the exome and whole genome, what it is and what it is used for; a discussion in proteomics of mass spectrometry; and in the gene therapy section references to CrispR technology; RNA sequencing and the re-evaluation of GWAS studies.
• Biochemistry and cell biology chapter: a full update of the introductory text on cells and tissues including the newly discovered organelles and their intracellular organisation; additional text on morphogenesis, and morph-omics; additional text demonstrating the barriers in the eye, flow of fluid within the eye and the biochemistry of corneal collagen crosslinking.
• Physiology of vision chapter: an increase in the coverage of anatomy of the cranial nerves will be combined with the relevant material on neurophysiology in this chapter. In addition there will be new material relating to clock genes and effects on visual function, non-ocular photoreception, and new studies on extensive parcellation in the brain will be included.
• Pharmacology chapter: revision of this chapter will include updates in the ocular pharmacology and drug delivery sections.
• Immunology chapter: a major revision of this section will transfer appropriate material to the eBook; in addition there will be updates on ocular immunology eg inflammation in AMD and glaucoma.
• Infection chapter: there will be new information on viruses such as Ebola, Zika, Chikungunya, CMV in immunocompetent individuals and Dengue.
• Pathology chapter: There will be updates of terminology / definition of vasculitis pathology; and new text on "liquid biopsy" emphasising optimal handling of sample delivery to the pathologist.

Key Features

• The only all-embracing textbook of the basic sciences suitable for trainee ophthalmologists, optometrists and vision scientists.
• Utilising an attractive page design with over 300 colour drawings and 200 photographs this is an attractive and accessible text to learn from.
• The text presents in a readable form an account of all the basic sciences necessary for an understanding of the eye – anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology.

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