Surgery, Basic Science and Clinical Evidence

* A new edition of an instant classic
* Features fully revised and updated information on the evidence-based practice of surgery
* Includes significant new sections on trauma and critical care on the often challenging surgical care of unique populations

"…the ambitious undertaking of creating an evidence-based textbook of surgery has largely succeeded and I heartily recommend it. Surgery: Basic Science and Clinical Evidence have something for everyone, from the newest surgical resident to the established surgeon in practice." JAMA on the First Edition

"During a period of numerous adventures in the textbook arena, this is different in focus and quality…reader friendly with excellent illustrations and 200 evidence-based tables" Archives of Surgery on the First Edition

"The text is clearly written, and the chapters are well illustrated...Chief residents in surgery preparing for their board examinations will find this book especially helpful, because the chapters deal in a comprehensive way with the nine major areas of general surgery identified by the American Board of Surgery." New England Journal of Medicine on the First Edition

"…a strong text for the general surgeon, regardless of training status, academic affiliation, or practice venue. There is much here for everyone. The work is current, fairly complete, objective, and very readable compared with other general surgical textbooks." Surgical Infections on the First Edition.

The second edition of Surgery: Basic Science and Clinical Evidence features fully revised and updated information on the evidence-based practice of surgery, significant new sections on trauma and critical care on the often challenging surgical care of unique populations; (elderly, pediatric, immunocompromised, and obese patients). The internationally recognized editors and authors have maintained their evidence-based approach throughout the text with thoughtful and timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics, and discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. The oft-cited chapter on the principles of evidence-based decision-making in surgical practice is completely updated for the second edition, presenting the reader with a framework for the evidence-based practice of surgery.

The First Edition’s strong emphasis on the basic science underlying the practice of surgery is upheld, providing readers with solid preparation for inservice and recertification examinations. Clinically focused sections in gastrointestinal, vascular, cardiothoracic, transplant, and cancer surgery enable the surgeon to make decisions based upon the most relevant data. The text is enhanced by more than 1,000 illustrations and hundreds of the signature evidence-based tables that made the first edition of SURGERY an instant classic. With is strong basic science coverage and emphasis on evidence-based decision making, the Second Edition is required reading for all general surgery trainees, practitioners, and surgical subspecialists.


Table of contents

1. Origins of Modern Surgery.- 2. Evidence-Based Surgery.- 3. Cell Structure, Function, and Genetics.- 4. Mediators of Inflammation and Injury.- 5. Substrate Metabolism.- 6. Nutrition.- 7. Perioperative Fluids and Electrolytes.- 8. Hemostasis and Coagulation.- 9. Transfusion Therapy.- 10. Wounds: Biology and Management.- 11. Diagnosis and Management of Infection.- 12. Infections of Soft Tissue.- 13. Intraabdominal Infections.- 14. Nosocomial Infections.- 15. Severe Sepsis and Septic Shock.- 16. Shock and Resusitation.- 17. Perioperative Management.- 18. Anesthesia.- 19. Pain Management.- 20. The Development of Trauma and Critical Care.- 21. Trauma Systems, Triage, and Disaster Management.- 22. Monitoring Techniques, Procedures, and Complications.- 23. Imaging of the Critically ill Patient.- 24. Risk Prediction and Outcomes.- 25. Burns and Inhalation Injury.- 26. Trauma to the Head and Neck.- 27. Trauma to the Torso.- 28. Trauma to the Pelvis and Extremities.- 29. Vascular Injuries.- 30. Spinal Injuries.- 31. Multiple Organ Dysfunction Syndrome.- 32. Principles of Mechanical Ventilation.- 33. Renal Replacement Therapy.- 34. The Open Abdomen.- 35. Principles of Rehabilitation.- 36. Surgical Care of the Pediatric Patient.- 37. Surgical Care of the Geriatric Patient.- 38. Clinical Issues in Managing the HIV-Infected Patient.- 39. Surgical Care of the Obese Patient.- 40. Surgical Care of the Pregnant Patient.- 41. History of Surgery f the Gastrointestinal Tract.- 42. Assessment of Acute Abdominal Symptoms.- 43. General Principles of Minimally Invasive Surgery.- 44. Esophagus.- 45. Stomach and Duodenum.- 46. Pancreas.- 47. Biliary System.- 48. Liver.- 49. Samll Intestine.- 50. Appendix.- 51. Colon, Rectum, and Anus.- 52. Spleen.- 53. Hernias and Abdominal Wall Defects.- 54. History of Endocrine Surgery.- 55. Parathyroid.- 56. Thyroid.- 57. Adrenal.- 58. Neuroendocrine Tumors of Pancreas, GI Tract, and Carcinoid.- 59. Multiple Endocrine Neoplasia.- 60. History of Vascular Surgery.- 61. Pathobiology of Vascular Disease.- 62. Cerebrovascular Disease.- 63. Diseases of Thoracic Aorta.- 64. Diseases of the Great Vessels.- 65. Diseases of the Abdominal Aorta and its Branches.- 66. Arterial Disease of the Lower Extremity.- 67. Venous Disease and Pulmonary Embolism.- 68. Vascular Access for Dialysis, Nutrition, and Chemotherapy.- 69. History of Cardiac Surgery.- 70. Pre- & Post-Op Care of the Thoracic Surgery Patient.- 71. Lung Neoplasms.- 72. Thoracic and Pulmonary Infections.- 73. Video-Assisted Thoracic Surgery.- 74. Pleura and Pericardium.- 75. Mediastinum.- 76. Congenital Heart Disease.- 77. Adult Heart Disease.- 78. Mechanical Circulatory Support.- 79. History of Transplantation.- 80. Immunology of Transplantation.- 81. Rejection.- 82. Organ Preservation.- 83. Kidney Transplantation.- 84. Pancreas and Islet Cell Transplantation.- 85. Transplantation of the Liver.- 86. Transplantation of the Intestine.- 87. Lung Transplantation.- 88. Heart Transplantation.- 89. History of Surgical Oncology.- 90. Genetics of Cancer.- 91. Fundamentals of Cancer Genomics and Proteomics.- 92. Fundamentals of Cancer Cell Biology and Molecular Targeting.- 93. Immunology of Cancer.- 94. Principles of Cancer Surgery.- 95. Principles of Radiation Therapy.- 96. Benign and Malignant Diseases of the Breast.- 97. Melanoma and Other Cutaneous Malignancies.- 98. Soft Tissue Sarcoma.- 99. GIST Tumors.- 100. Head and Neck Malignanices.- 101. Surgical Emergencies in the Cancer Patient.- 102. Nutritional Care of the Cancer Patients.- 103. Regional Therapy of Cancer.- 104. End-of-Life Care.- 105. Urology.- 106. Gynecology.- 107. Neurosurgery.- 108. Orthopedics.- 109. Plastic Surgery.

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