PRINCIPLES OF DEVELOPMENTAL GENETICS

Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.

Audience
Advanced molecular, cell, developmental biologists and developmental geneticists, and clinical geneticists

Contents


I. The Impact of Genetic and Genomic Tools on Developmental Biology
1. Untangling the Gordian knot: Cell Signaling Events that Instruct Development Philippe Soriano and Renee V. Hoch 2. Finding Gene Expression Changes using Microarray Technology Tadayoshi Hayata and Ken W.Y. Cho 3. Chemical and Functional Genomic Approaches to Study Stem Cell Biology and Regeneration Wen Xiong and Sheng Ding 4. Assessing Neural Stem Cell Properties using Large Scale Genomic Analysis Soojung Shin, Jonathan D. Chesnut and Mahendra S. Rao 5. Epigenetic Influences on Gene Expression Pathways Sundeep Kalantry and Terry Magnuson 6. New Insights into Vertebrate Origins Billie J. Swalla 7. Understanding Human Birth Defects Through Model Organism Studies Feyza Engin and Brendan Lee

II. Early Embryology, Fate Determination and Patterning
8. Germ Line Determinants and Oogenesis Kelly M Haston and Renee A Reijo Pera 9. Patterning the Anterior-Posterior Axis during Drosophila Embryogenesis Kristy L. Kenyon 10. Anterior-Posterior Patterning in Mammals Sigolene M. Meilhac 11. Signaling Cascades, Gradients, and Gene Networks in Dorsal/Ventral Patterning Girish S. Ratnaparkhi and Albert J. Courey 12. Early Development of Epidermis and Neural Tissue Keiji Itoh and Sergei Y. Sokol 13. Formation of the Embryonic Mesoderm Lisa L. Chang and Daniel S. Kessler 14. Endoderm Debora Sinner, James M Wells and Aaron M. Zorn 15. Notch Signaling – A Versatile Tool for the Fine Patterning of Cell Fate in Development Ajay B. Chitnis 16. Multiple roles of T-box genes L. A. Naiche and Virginia E. Papaioannou

III. Morphogenetic and Cell Movements
17. Gastrulation in Vertebrates Lilianna Solnica-Krezel and Diane S. Sepich 18. Regulation of tissue separation in the amphibian embryo Herbert Steinbeisser 19. Role of the Basement Membrane in Cell Migration Kiyoji Nishiwaki, Kiyoji Nishiwaki and Yukihiko Kubota 20. Epithelial Morphogenesis Ronit Wilk and Howard D. Lipshitz 21. Branching Morphogenesis of Mammalian epithelia Jamie Davies 22. The Roles of Ephrin-Eph in Morphogenesis Ira O. Daar

IV. Ectodermal Organs
23. Neural Cell Fate Determination Stephen N. Sansom and Frederick J. Livesey 24. Pathfinding and Patterning of Axonal Connections S.A Linn, S.R. Kadison and C.E. Krull 25 Retinal Development Kathryn B. Moore and Monica L. Vetter 26. Neural Crest Determination Roberto Mayor 27. Determination of Pre-Placodal Ectoderm and Sensory Placodes Sally A. Moody 28. Molecular Genetics of Tooth Development Irma Thesleff 29. The Inner Ear Donna F. Fekete and Ulrike J. Sienknecht 30. Craniofacial Formation and Congenital Defects S.A. Brugmann and J.A. Helms

V. Mesodermal Organs
31. Induction of the Cardiac Lineage Andrew S. Warkman and Paul A. Krieg 32. Heart Patterning and Congenital Defects John Belmont 33. Blood Vessel Formation Karina Yaniv and Brant M. Weinstein 34. Blood Induction and Embryonic Formation Xiaoying Bai and Leonard I. Zon 35. Topics in Vertebrate Kidney Formation: A Comparative Perspective Thomas M. Schultheiss 36. Development of The Genital System Hongling Du & Hugh S Taylor 37. Diaphragmatic Embryogenesis and Human Congenital Diaphragmatic Defects Kate G. Ackerman and David R. Beier 38. Formation of Vertebrate Limbs Yingzi Yang 39. Skeletal Development Peter G. Alexander, Amanda T. Boyce, and Rocky S. Tuan

VI. Endodermal Organs
40. Patterning the Embryonic Endoderm into Presumptive Organ Domains Billie A. Moore-Scott and James M. Wells 41. Developmental Genetics of the Pulmonary System Thomas J. Mariani 42. Pancreas Development and Stem Cells Maureen Gannon 43. Early Liver Development and Hepatic Progenitor Cells Jay D. Kormish and Kenneth S. Zaret 44. Intestinal Stem Cells in Physiologic Regeneration and Disease David H. Scoville, Xi C. He, Goo Lee, Toshiro Sato, Terrence A. Barrett, and Linheng Li

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