Postgraduate Haematology

The textbook of choice for trainees and practitioners in haematology! Over five editions Postgraduate Haematology has built a reputation as an extremely practical, user-friendly, reliable source of information for examination preparation and clinical practice. Completely revised to reflect the latest research in the field, this edition continues to provide trainees with up-to-date knowledge on the pathogenesis, clinical and laboratory features, and management of blood disorders. It covers the significant advances which have occurred in the application of cytogenetics and molecular genetics in the diagnosis, classification and understanding of haematological disorders. Coupled with the expertise of 34 new contributors from across Europe, the editors have been joined by Professor Anthony Green, from the University of Cambridge, and they have reorganised the book into 52 accessible chapters. Postgraduate Haematology is richly illustrated throughout with over 450 colour illustrations including line drawings, photomicrographs of blood cells and tissues, and algorithms to help aid treatment decision making. It is an indispensable resource for trainees and an essential read for all specialists who are interested in updating their knowledge. Companion resources site for this book: www. wiley. com/go/hoffbrand/postgraduate with: Figures and tables from the book for downloading Interactive multiple-choice questions Contributors. Preface to the sixth edition. Preface to the first edition. Chapter 1 Stem cells and haemopoiesis (Elaine Dzierzak). Chapter 2 Erythropoiesis (Douglas R. Higgs and William G. Wood). Chapter 3 Iron metabolism, iron deficiency and disorders of the haem synthesis (A. Victor Hoffbrand, Chaim Hershko and Clara Camaschella). Chapter 4 Iron overload (Clara Camaschella and A. Victor Hoffbrand). Chapter 5 Megaloblastic anaemia (A. Victor Hoffbrand). Chapter 6 Haemoglobin and the inherited disorders of globin synthesis (Swee Lay Thein and David Rees). Chapter 7 Sickle cell anaemia (Ashutosh Lal and Elliott P. Vinchinsky). Chapter 8 Hereditary disorders of the Red cell membrane (Edward C Gordon-Smith and Narla Mohandas). Chapter 9 Disorders of Red cell metabolism (Alberto Zanella and Edward C. Gordon-Smith). Chapter 10 Acquired haemolytic anaemia (Edward C Gordon-Smith and Modupe O Elebute). Chapter 11 Paroxysmal nocturnal haemoglobinuria (Peter Hillmen). Chapter 12 Inherited aplastic anaemia / bone marrow failure syndromes (Inderjeet S. Dokal). Chapter 13 Acquired aplastic anaemia (Judith CW Marsh and Neal S Young). Chapter 14 Red cell immunohaemotology: introduction (Marcelo Contreras and Geoff Daniels). Chapter 15 Antigens in human blood (Marcelo Contreras and Geoff Daniels). Chapter 16 Clinical blood transfusion (Marcelo Contreras, Clare P. F Taylor and John A. Barbara). Chapter 17 Phagocytes (John Mascarenhas, Farhad Ravandi and Ronald Hoffman). Chapter 18 Lysosomal storage disorders (Atul B. Metha and Derralynn A. Hughes). Chapter 19 Normal Lymphocytes and non-neoplastic lymphocyte disorders (Paul A. H. Moss). Chapter 20 The Spleen (Paul A. H. Moss and Mark T. Drayson). Chapter 21 Molecular basis of leukaemia and lymphoma (George Vassilios and Anthony R. Green). Chapter 22 Laboratory diagnosis of haematological neoplasms (Barbara J. Bain and Torsten Haferlach). Chapter 23 Acute myeloid leukaemia (Alan K. Burnett and Adriano Venditti). Chapter 24 Acute lymphoblastic leukaemia in adult (Dieter Hoelzer and Nicola Gökbuget). Chapter 25 Acute lymphoblastic leukaemia in children (Dario Campana and Ching-Hon Pui). Chapter 26 Supportive care in the management of leukaemia (Archibald G. Prentice and J. Peter Donnelly). Chapter 27 Chronic myeloid leukaemia (John M. Goldman and Tariq I. Mughal). Chapter 28 The Myelodysplastic syndromes (Timothy J. T. Chevassut and Ghulam J. Mufti). Chapter 29 Chronic lymphocytic leukaemia and other B-cell disorders (Daniel Catovsky and Emili Montserrat). Chapter 30 T-cell lymphoproliferative disorders (Estella Matutes). Chapter 31 Multiple myeloma (Jesús San-Miguel and Joan Bladé). Chapter 32 Amyloidosis (Simon D. J. Gibbs and Philip N. Hawkins). Chapter 33 Classification of lymphoma: updating the WHO classification (Elias Campo and Stefano A. Pileri). Chapter 34 Hodgkin’s disease (David Linch and co-author). Chapter 35 Non-Hodgkin’s disease Lymphoma (Kate Cywnarski and Anthony H. Goldstone). Chapter 36 Myeloproliferative neoplasms (Peter J. Campbell and Anthony. R. Green). Chapter 37 Histocompatability (Ann-Margaret Little, Steven G. E. Marsh and J. Alejandro Madrigal). Chapter 38 Stem cell transplantation (Charles Craddock and Ronjon Chakraverty). Chapter 39 Normal haemostasis (Keith Gomez, Edward G. D. Tuddenham, and John H. McVey). Chapter 40 Vascular Function of Platelets (Stephen P. Watson and Paul Harrison). Chapter 41 Inherited bleeding disorders (Michael A. Laffan and K. John Pasi). Chapter 42 Rare bleeding disorders (Flora Peyvandi and Marzia Menagatti). Chapter 43 Acquired coagulation disorders (Peter Collins and Cheng Hok Toh). Chapter 44 Thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome (congenital and acquired) (Pier M Mannucci, Flora Peyvandi and Roberta Palla). Chapter 45 Heritable thrombophilia (Trevor Baglin). Chapter 46 Acquired venous thrombosis (Beverley J. Hunt and Michael Greaves). Chapter 47 Management of venous thrombosis (Beverly J. Hunt). Chapter 48 Congenital platelet disorders (Maurizio Margagkione and Paul R. J. Ames). Chapter 49 Immune thrombocytopenia (Drew Provan and Adrian C. Newland). Chapter 50 Hematological aspects of systemic disease (Atul B. Mehta and A. Victor Hoffbrand). Chapter 51 Hematological aspects of tropical diseases (Imelda Bates and Ivy Ekem). Chapter 52 Pediatric and neonatal haematology (Irene A. G. Roberts). Appendix I Normal Values. Appendix II WHO classification of haematological diseases.