Pathology Oxidative Stress and Dietary Antioxidants

Pathology: Oxidative Stress and Dietary Antioxidants bridges the disciplinary knowledge gap to help advance medical sciences and provide preventative and treatment strategies for pathologists, health care workers, food scientists and nutritionists who have divergent skills. This is important as oxidative stress can be ameliorated with pharmacological, nutraceutical or natural agents. While pathologists and clinical workers understand the processes in disease, they are less conversant in the science of nutrition and dietetics. Conversely, nutritionists and dietitians are less conversant with the detailed clinical background and science of pathology. This book helps to fill those gaps.

• Saves clinicians and researchers time by helping them to quickly access the very latest details on a broad range of pathologies and oxidation issues
• Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet
• Includes preclinical, clinical and population studies to help pathologists, nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations

Table of Contents

Preface

I. Oxidative Stress and Pathology  

1. Free radicals: what they are and what they do
EVA TVRDÁ AND FILIP BENKO

2. Oxidative stress in pathologies of male reproductive disorders
ASHOK AGARWAL, KRISTIAN LEISEGANG AND PALLAV SENGUPTA

3. Oxidative stress and diabetic retinopathy
KEMAL TEKIN AND MERVE INANC TEKIN

4. Pathological bases of oxidative stress in the development of cardiovascular diseases
MARIANE RÓVERO COSTA, JÉSSICA LEITE GARCIA, CAROL CRISTINA VÁGULA DE ALMEIDA SILVA, ANA PAULA COSTA RODRIGUES FERRAZ, FABIANE VALENTINI, FRANCISQUETI-FERRON, ARTUR JUNIO TOGNERI FERRON AND CAMILA RENATA CORRÊA

5. Pathological association between oxidative stress and chronic obstructive pulmonary disease
MAHMOOD A. AL-AZZAWI

6. Oxidative stress in sickle cell disease and emerging roles for antioxidants in treatment strategies
YEŞIM ÖZTAŞ AND İFFET İPEK BOŞGELMEZ

7. Nrf2 and oxidative stress
OSAMU WADA-HIRAIKE

8. Redox signaling and antioxidant defense in pathogenic microorganisms: a link to disease and putative therapy
ARISTIDIS S. VESKOUKIS

9. Paraoxonase 1 as antioxidant enzyme in children
MAXIMILIANO MARTÍN, VALERIA HIRSCHLER, ELIANA BOTTA AND FERNANDO BRITES

10. The regulation of intracellular redox homeostasis in cancer progression and its therapy
PRITAM SADHUKHAN AND PARAMES C. SIL

II. Antioxidants and Pathology  

11. Antioxidant and chelator cocktails to prevent oxidative stress under iron-overload conditions
SIRINART KUMFU, SIRIPORN CHATTIPAKORN AND NIPON CHATTIPAKORN

12. Açaí (Euterpe oleracea Martius) as an antioxidant
PRISCILA OLIVEIRA BARBOSA, MELINA OLIVEIRA DE SOUZA, DANIELA PALA AND RENATA NASCIMENTO FREITAS

13. Amaryllidaceae alkaloids and neuronal cell protection
NATALIE CORTES, RAFAEL POSADA-DUQUE, GLORIA PATRICIA CARDONA-GÓMEZ, JAUME BASTIDA AND EDISON OSORIO

14. Anthocyanins and anthocyanin-rich food as antioxidants in bone pathology
JUNICHI R. SAKAKI, MELISSA M. MELOUGH AND OCK K. CHUN

15. Ascorbic acid as an antioxidant and applications to the central nervous system
MORGANA MORETTI AND ANA LÚCIA S. RODRIGUES

16. Artichoke leaf extract and use in metabolic syndrome as an antioxidant
KHATEREH REZAZADEH AND MEHRANGIZ EBRAHIMI-MAMEGHANI

17. Bilberry anthocyanins as agents to address oxidative stress
JERRY T. THORNTHWAITE, SETH P. THIBADO AND KYLE A. THORNTHWAITE

18. Clitoria ternatea beverages and antioxidant usage
SIRICHAI ADISAKWATTANA, PORNTIP PASUKAMONSET AND CHAROONSRI CHUSAK

19. Curcumin and related antioxidants: applications to tissue pathology
CAROLINA ALVES DOS SANTOS, MAHENDRA RAI, JOSÉ MARTINS DE OLIVEIRA JR, FERNANDO DE SÁ DEL FIOL, ROGERIO AUGUSTO PROFETA, DENICEZAR BALDO MARCO AND MARCO VINÍCIUS CHAUD

20. Dacryodes edulis: protective antioxidant effects on diabetes pathology
OLAKUNLE SANNI, OCHUKO L. ERUKAINURE AND MD. SHAHIDUL ISLAM

21. Protective role of epigallocatechin gallate, a dietary antioxidant against oxidative stress in various diseases
PUNNIYAKOTI VEERAVEEDU THANIKACHALAM, SRINIVASAN RAMAMURTHY, ANOOP KUMAR, MEENAKSHI GUPTA AND GARIMA BANSAL

22. Extra virgin olive oil polyphenols: biological properties and antioxidant activity
ANNALISA SILENZI, CLAUDIO GIOVANNINI, BEATRICE SCAZZOCCHIO, ROSARIA VARÌ, MASSIMO D’ARCHIVIO, CARMELA SANTANGELO AND ROBERTA MASELLA

23. Ginkgo biloba extract as an antioxidant in nerve regeneration
NAHIDE EKICI-GÜNAY

24. Lycopene as an antioxidant in human health and diseases
HATICE GÜL ANLAR AND MERVE BACANLI

25. Mediterranean diet: the role of antioxidants in liver disease
LUDOVICO ABENAVOLI, LORENZO ROMANO, PAOLA GUALTIERI, GEMMA LOU DE SANTIS AND ANTONINO DE LORENZO

26. Melatonin, antioxidant capacity, and male reproductive function
FAHIMEH MOHAMMADGHASEMI

27. Methylsulfonylmethane as an antioxidant and its use in pathology
MATTHEW BUTAWAN, RODNEY L. BENJAMIN AND RICHARD J. BLOOMER

28. Improving antioxidant capacity of foods: adding mushroom powder to pasta
LIWEN WANG, MARGARET ANNE BRENNAN AND CHARLES STEPHEN BRENNAN

29. Phenolics: therapeutic applications against oxidative injury in obesity and type 2 diabetes pathology
VERONICA F. SALAU, OCHUKO L. ERUKAINURE AND MD. SHAHIDUL ISLAM

30. Pistachio nut, its virgin oil, and their antioxidant and bioactive activities
MARÍA DESAMPARADOS SALVADOR, ROSA M. OJEDA-AMADOR AND GIUSEPPE FREGAPANE

31. Sambucus ebulus L., antioxidants and potential in disease
ALEKSANDRA CVETANOVIĆ

32. Selenium usage and oxidative stress in Graves’ disease and Graves’ orbitopathy
MICHELE MARINÒ, GIULIA LANZOLLA, GIOVANNA ROTONDO DOTTORE AND CLAUDIO MARCOCCI

33. Antioxidant potential of Stevia rebaudiana (Bertoni)
KASHIF AMEER, GUI-HUN JIANG, RAI MUHAMMAD AMIR AND JONG-BANG EUN

34. Tea antioxidants in terms of phenolic and nonphenolic metabolites
PROTIVA RANI DAS AND JONG-BANG EUN

35. Thymoquinone: the active compound of black seed (Nigella sativa)
HATICE GÜL ANLAR AND MERVE BACANLI

36. Yacon (Smallanthus sonchifolius) use as an antioxidant in diabetes
ANA PAULA COSTA RODRIGUES FERRAZ, JÉSSICA LEITE GARCIA, MARIANE RÓVERO COSTA, CAROL CRISTINA VÁGULA DE ALMEIDA, CRISTINA SCHIMITT GREGOLIN, PEDRO HENRIQUE RIZZI ALVES, FABIANA KUROKAWA HASIMOTO, CAROLINA B. BERCHIERI-RONCHI, KLINSMANN CAROLO DOS SANTOS AND CAMILA RENATA CORRÊA

III. Techniques and Resources

37. Screening procedures and tests for antioxidants
JAN BORLINGHAUS, JANA REITER, MICHAEL RIES AND MARTIN C. H. GRUHLKE

38. Recommended resources for pathology: oxidative stress and dietary antioxidants
RAJKUMAR RAJENDRAM, VINOOD B. PATEL AND VICTOR R. PREEDY 

REVIEW-URI