Organ Repair and Regeneration Preserving Organs in the Regenerative Medicine Era

Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation. 

• Covers all aspects of organ preservation, repair and regeneration
• Addresses the repair of organs that experience an Ischemia/Reperfusion (I/R) injury, those that are intended for transplantation, and specific issues related to each organ
• Presented by editors and authors who are physicians, surgeons and researchers in the field of organ transplantation and regenerative medicine

Table of Contents

1. Pathophysiology of Ischemia-Reperfusion 
   Natasha Rogers, Wayne Hawthorne, Jennifer Li
   2. Marginal Organs Repair: From Vision to Every Day Clinical Practice
   Robert Porte
   3. Assessing and reconditioning kidneys using normothermic machine perfusion 
   Michael Nicholson
   4. Autologous cells for renal allograft repair  
   Mark Clancy
   5. Repairing organs with MSC  
   Lauren Brasile
   6. Repairing the marginal pancreas
   Wayne Hawthorne
   7. Assessment of marginal Liver grafts during machine perfusion- How far can we go? 
   Markus Selzner
   8. RNA interference in organ transplantation: next generation medicine? 
   Paulo Martins
   9. Repairing cardiac allografts on ex situ perfusion devices   
   Peter Macdonald
   10. Repairing cardiac allografts in situ
   Stephen Large, Simon Messer, Oscar Zou
   11. VCA Organ Repair: possibilities and next steps 
   Korkut Uygun
   12. Implementing the Vision: The Organ Repair Center 
   Shaf Keshavjee
   13. Mitochondria Transplantation in Organ Damage and Repair 
   Benedetta Bussolati
   14. Conclusion
   Giuseppe Orlando

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