Molecular Biology

Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves.

Moreover, as part of the Academic Cell line of textbooks, this book contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles form the basis of case studies found in the associated online study guide that is designed to tie current topics to the scientific community.

Key Features

• Contains new chapters on non-coding RNA, genome defense, epigenetics and epigenomics
• Features new and expanded coverage of RNAi, CRISPR, genome editing, giant viruses and proteomics
• Includes an Academic Cell Study Guide that ties all articles from the text with concurrent case studies
• Provides an updated, ancillary package with flashcards, online self-quizzing, references with links to outside content, and PowerPoint slides with images

Readership

Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and agriculture

Table of Contents

Unit 1: Basic Chemical and Biological Principles
1. Cells and Organisms
2. Basic Genetics
3. DNA, RNA, and Protein
4. Genes, Genomes, and DNA
5. Manipulation of Nucleic Acids

Unit 2: The Genome
6. The Polymerase Chain Reaction
7. Cloning Genes for Analysis
8. DNA Sequencing
9. Genomics and Systems Biology
New Chapter to cover metagenomics, symbiosis, epigenomics etc

Unit 3: The Central Dogma of Molecular Biology
10. Cell Division and DNA Replication
11. Transcription of Genes
12. Processing of RNA (moved to Unit 4)
13. Protein Synthesis
14. Protein Structure and Function
15. Proteomics: Global Analysis of Proteins

Unit 4: Regulating Gene Expression
16. Regulation of Transcription in Prokaryotes
17. Regulation of Transcription in Eukaryotes
12. Processing of RNA (moved from Unit 3)
18. Regulation at the RNA Level
New Chapter on Genome defense (RNAi and CRISPR). Would include their use in genetic analysis and genome editing
19. Analysis of Gene Expression (Transcriptome)

Unit 5: Subcellular Life Forms
20. Plasmids
21. Viruses
22. Mobile DNA

Unit 6: Changing the DNA Blueprint
23. Mutations and Repair
24. Recombination
25. Bacterial Genetics
26. Molecular Evolution