Metabolic Therapies in Orthopedics

The first medical reference textbook to compile an unprecedented synthesis of evidence for regenerative orthopedics by key opinion leaders

Thirty-five authors address your clinical questions

What emerging technologies are right for my clinical practice? How can I strengthen my patients before their orthopedic surgery? Practically speaking, how can I leverage the latest metabolic therapies to safeguard my patients from toxins, medications, food and chronic diseases known to adversely affect the musculoskeletal system?

"Ask the Author" feature

Would you like to discuss a patient with a particular author? Now you can do so at www. betterorthopedics. com.

First to be second

Did you notice this book is the first book in regenerative orthopedics to publish a second edition? This diverse author team leads the growing field of regenerative orthopedics and offers the broadest and in-depth approach to leveraging metabolic therapies.

This book comprises the professional opinion of its authors. It does not claim to represent guidelines, recommendations, or the current standard of medical care.

Table of Contents

Contents

Preface... ix

Acknowledgments... xi

Editors... xiii

Contributors... xv

Section I Cross-Cutting Technologies

Chapter 1 Regenerative Orthopedics Enabled by Cross-Cutting Technologies... 3

Kenneth Cintron, MD, MBA

Chapter 2 Orthogenomics: Genome-Directed Therapies in Orthopedics... 21

Joseph R. Veltmann, PhD, DCCN and Roberta L. Kline, MD

Chapter 3 Predictive Biomarkers in Personalized Laboratory Diagnoses and Best

Practices Outcome Monitoring for Musculoskeletal Health... 39

Russell Jaffe MD, PhD, CCN and Jayashree Mani, MS, CCN

Chapter 4 Veterinary Medicine’s Advances in Regenerative Orthopedics... 59

Sophie H. Bogers, BVSc, MVSc, PhD and Jennifer G. Barrett, DVM, PhD

Chapter 5 Biotensegrity: How Ultrasound Diagnostics Guide Regenerative Orthopedic

Therapies to Restore Biomechanical Function... 93

Bradley D. Fullerton, MD

Chapter 6 Photobiomodulation Therapy in Orthopedics: Metabolic Effects... 113

Michael R. Hamblin, PhD

Section II Clinical Approaches to Preventing

and Treating Metabolic Dysfunction

Chapter 7 Safeguarding Musculoskeletal Structures from Food Technology’s Untoward

Metabolic Effects... 141

Ingrid Kohlstadt, MD, MPH

Chapter 8 Inflammatory Responses Acquired Following Environmental Exposures Are

Involved in Pathogenesis of Musculoskeletal Pain... 159

Ritchie C. Shoemaker, MD and James C. Ryan, PhD

Chapter 9 Periodontal Disease: Treatable, Nutrition-Related, and with Systemic

Repercussions... 185

David Kennedy, DDS

Chapter 10 Reduction in Orthopedic Conditions through Teledontic Treatment of

Pharyngorofacial Disorders... 193

Joseph Yousefian, DMD, MS and Michael N. Brown, DC, MD

Chapter 11 Drug-Related Muscular Pain... 215

Sahar Swidan, PharmD

Chapter 12 Metabolic Interventions for Sarcopenic Obesity... 223

Gabrielle Lyon, DO and Jamie I. Baum, PhD

Chapter 13 Drug-Related Sarcopenia... 239

Sahar Swidan, PharmD

Chapter 14 Sex Hormones and Their Impact on Sarcopenia and Osteoporosis... 251

Pamela W. Smith, MD, MPH, MS

Chapter 15 Treating the Dysmetabolism Underlying Osteoporosis... 263

Xaviour Walker, MD, MPH, DTMH and Joseph Lamb, MD

Chapter 16 Nutritional Status and Interventions for Reducing Stress Fracture Risk among

Military Personnel... 283

James McClung, PhD

Section III Metabolic Therapies for

Specific Orthopedic Conditions

Chapter 17 Perioperative Metabolic Therapies in Orthopedics... 293

Frederick T. Sutter MD, MBA

Chapter 18 Metabolic Therapies for Muscle Injury... 319

Ana V. Cintrón, MD and Kenneth Cintron, MD, MBA

Chapter 19 Tendinopathy: Addressing the Chronic Pain and Pathophysiology... 339

David Musnick, MD

Chapter 20 Metabolic Therapies in the Management of Heel Pain... 349

Emily M. Splichal, DPM, MS

Chapter 21 Fascial Syndromes: Emerging, Treatable Contributors to Musculoskeletal Pain... 357

David Lesondak, BCSI, ATSI, FST, FFT

Chapter 22 Metabolic Approaches to the Treatment of Back Pain... 369

Carrie Diulus, MD and Patrick Hanaway, MD

Chapter 23 Optimizing Metabolism to Treat Fractures and Prevent Nonunion... 389

Jacob Wilson, MD, Scott Boden, MD, Kenneth Cintron, MD, MBA and

Mara Schenker, MD

Chapter 24 Treating the Underlying Causes of Synovitis, Degenerative Joint Disease and

Osteoarthritis in Primary Care... 403

John C. Cline, MD, BSc

Chapter 25 Osteoarthritis: Comprehensive Treatment... 419

David Musnick, MD and Richard D. Batson, ND

Chapter 26 Integrative Approaches to Autoimmune Arthritis... 449

George E. Muñoz, MD

Index... 465