Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management

Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management systematically examines the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This reference volume expands coverage of specific disorders and diseases beyond the current endocrinology content on the market, which in most cases has a paragraph or no mention at all about pregnancy or aspects of fetal/neonatal development.

• Formalized source of maternal/fetal endocrine physiology and pathophysiology
• Key reference for fellows and residents for rarer endocrine pathologies
• Integrated presentation of new molecular and genetic causes of endocrine disorders
• Bridges the experience/knowledge gap of endocrinopathies rarely encountered in pregnancy

Table of Contents

Section 1: THE MOTHER
A. Normal endocrine physiology of the mother during pregnancy and lactation
1. Hypothalamus
2. The pineal gland and its function in pregnancy and lactation
3. Pituitary
4. Physiology of the Thyroid during Pregnancy, Postpartum and Lactation
5. Physiology of Calcium, Phosphorus, and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning
6. Gestational Glucose Metabolism: Focus on the Role & Mechanisms of Insulin Resistance
7. Intestinal and neuroendocrine hormones
8. Adrenal cortex and medulla physiology during pregnancy, labor and puerperium
9. Ovarian Function During Pregnancy and Lactation
10. The physiological roles of the renin angiotensin aldosterone system and vasopressin in human pregnancy
11. Central role of adipose tissue in pregnancy and lactation
12. Hormonal regulation of the menstrual cycle and ovulation
13. Maintenance of pregnancy and parturition
14. Hormonal regulation of milk production
15. Postpartum Lactational Amenorrhea and Recovery of Reproductive Function and Normal Ovulatory Menstruation

B. Maternal endocrine disorders during pregnancy and lactation
16. Hypothalamic
17. Pineal
18. Pituitary disorders (hyper and hypofunction, tumors)
19. Thyroid (hyperthyroidism, hypothyroidism)
20. Thyroid Cancer during Pregnancy and Lactation
21. Disorders of Mineral and Bone Metabolism During Pregnancy and Lactation
22. Gestational and type 2 diabetes
23. Type 1 Diabetes: During preconception, pregnancy, postpartum, breastfeeding
24. Gut and pancreatic neuroendocrine tumors in pregnancy and lactation
25. Adrenal pathologies during pregnancy and post-partum
26. Hypertension in pregnancy
27. Obesity

C. Other
28. Fertility, pregnancy, and chest feeding in transgendered individuals

Section 2: THE CHILD
D. Normal endocrine development and physiology of the fetus and neonate
29. Endocrinology of implantation
30. Hypothalamus and pituitary
31. Pineal
32. Thyroid
33. Physiology of Calcium, Phosphorus, and Bone Metabolism During Fetal and Neonatal Development
34. Developmental Physiology of Carbohydrate Metabolism and the Pancreas
35. Developmental Origins and Roles of Intestinal Enteroendocrine Hormones
36. Adrenal cortex and medulla
37. Ovaries and Testes
38. Renin-angiotensin-aldosterone system and vasopressin
39. Origins of Adipose Tissue and Adipose Regulating Hormones
40. Fetal growth physiology
41. Placental production of steroid and peptide hormones

E. Endocrine disorders affecting the fetus or neonate
42. Hypothalamus and pituitary
43. Pineal
44. Thyroid (agenesis, hypothyroidism, fetal Graves’, etc.)
45. Disorders of Calcium, Phosphorus and Bone Metabolism During Fetal and Neonatal Development
46. Pancreas and carbohydrate metabolism (diabetes and hypoglycemia)
47. Intestinal enteroendocrine disorders
48. Adrenal disorders of the fetus and neonate
49. Disorders of Sex Differentiation
50. Renin-angiotensin-aldosterone and vasopressin
51. Obesity / perinatal origins of obesity
52. Fetal growth failure
53. New Technologies in Pre- and Post-natal Diagnosis