Hormones

Hormones, Fourth Edition provides a report on the field of human hormones viewed in light of our current understanding of cellular and subcellular architecture, along with the molecular details of their modes of action. Comprehensive information about hormone action on canonical and non-canonical signaling pathways at cellular and subcellular level and effects on architecture and function of organ systems are discussed. All chapters in this new edition have been completely updated to cover advances in endocrinology research, which has expanded significantly in the last few years. Vast coverage of hormones not previously covered and newly discovered aspects of hormone action are also included. This new fourth edition is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for health professionals, clinicians and researchers in the field of endocrinology, metabolism and biochemistry.

• Includes updates on all chapters
• Covers sleep hormones, growth factors, intestinal hormones, calcium-sensing receptor of parathyroid, and others
• Provides essential basics for advanced undergraduates, graduate students and researchers in the biological sciences, as well as clinical aspects and applications for clinicians
• Presented in separate hormone systems, covering the subcellular mode of action of selected hormones and a detailed understanding of their human anatomy and physiology

Table of Contents

• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• About the author
• Preface to the fourth edition
• Chapter 1. Hormones: an introduction
• Abstract
• I Overview of hormones
• II Hormone receptors
• III Mechanisms of hormone action
• IV Clinical aspects
• Further reading
• Chapter 2. Steroid hormones: chemistry, biosynthesis, and metabolism
• Abstract
• I Introduction
• II Chemistry of steroids
• III Biosynthesis of steroids
• IV Serum-binding proteins for steroid hormones
• Further reading
• Chapter 3. The hypothalamus and anterior pituitary
• Abstract
• I Introduction
• II Anatomical relationships
• III Structure, synthesis, secretion, and target cells of the hypothalamic releasing hormones
• IV Chemistry of the anterior pituitary hormones
• V Regulation and biological actions of growth hormone and prolactin
• VI The hypothalamus and appetite regulation
• VII Clinical aspects
• Further reading
• Chapter 4. Posterior pituitary hormones
• Abstract
• I Introduction
• II Anatomy of the posterior pituitary
• III Chemistry, biosynthesis, and secretion of the posterior pituitary hormones
• IV Biological actions of AVP
• V Biological actions of oxytocin
• VI Clinical aspects
• Further reading
• Chapter 5. Thyroid hormones
• Abstract
• I Introduction
• II Anatomy of the thyroid gland
• III Chemistry of the thyroid hormones
• IV Synthesis and secretion of thyroid hormones
• V Regulation of thyroid hormone secretion
• VI Biological actions of T3
• VII Clinical aspects
• Further reading
• Chapter 6. Pancreatic hormones: insulin and glucagon
• Abstract
• I Introduction
• II Anatomical, morphological, and physiological relationships
• III Chemistry, biochemistry, and biological activities of the pancreatic hormones
• IV Clinical aspects
• Further reading
• Chapter 7. Gastrointestinal hormones
• Abstract
• I Introduction
• II Anatomical and physiological relationships
• III Biochemical properties and molecular actions
• IV Clinical aspects
• Further reading
• Chapter 8. Eicosanoids
• Abstract
• I Introduction
• II Structure and nomenclature of eicosanoids
• III Synthesis and inactivation of eicosanoids
• IV Eicosanoid receptors and signaling
• V Examples of biological actions of prostaglandins
• VI Clinical aspects
• Further reading
• Chapter 9. Calcium-regulating hormones: vitamin D, parathyroid hormone, calcitonin, and fibroblast growth factor 23
• Abstract
• I Introduction
• II Anatomical and physiological relationships
• III Chemistry and biochemistry
• IV Biology and molecular actions
• V Clinical aspects
• Reference
• Further reading
• Chapter 10. Adrenal corticoids
• Abstract
• I Introduction
• II Anatomy
• III Biochemistry and biosynthesis of adrenal steroids and testosterone steroids
• IV Biological and molecular actions of glucocorticoids
• V Clinical aspects
• Further reading
• Chapter 11. Hormones of the adrenal medulla
• Abstract
• I Introduction
• II Anatomical and physiological relationships
• III Chemistry and biochemistry of the catecholamines
• IV Biological actions of catecholamines
• V Clinical aspects
• Further reading
• Chapter 12. Androgens
• Abstract
• I Introduction
• II Anatomy of the male reproductive system
• III Chemistry and metabolism of androgens
• IV Regulation of androgen production
• V Biological responses to androgens
• VI Clinical aspects
• Further reading
• Chapter 13. Estrogens and progestins
• Abstract
• I Introduction
• II Anatomy of the female reproductive system
• III Chemistry and metabolism of female steroid hormones
• IV Hypothalamic–pituitary–ovary axis
• V Biological responses to female sex steroids
• VI Clinical aspects
• Further reading
• Chapter 14. Hormones of pregnancy, parturition, and lactation
• Abstract
• I Introduction
• II Anatomical relationships and the beginning of pregnancy
• III Chemistry, biochemistry, and activity of the hormones of pregnancy
• IV Parturition
• V Lactation
• VI Clinical aspects
• Further reading
• Chapter 15. Hormones related to the kidney and cardiovascular system
• Abstract
• I Introduction
• II Anatomical, morphological, and physiological relationships
• III Homeostasis of fluid, electrolytes, and blood pressure
• IV Hormones and blood cell production
• V Clinical aspects
• Further reading
• Chapter 16. The pineal gland
• Abstract
• I Introduction
• II Anatomical features of the pineal gland
• III Synthesis and secretion of melatonin
• IV Biological actions of melatonin
• V Clinical aspects
• Further reading
• Chapter 17. Growth factors
• Abstract
• I Introduction
• II Epidermal growth factor
• III Fibroblast growth factor family
• IV Platelet-derived growth factors
• V Insulin-like growth factors
• VI Transforming growth factor β
• VII Clinical aspects
• Further reading
• Appendix 1. Compilation of many known hormones in higher mammals and humans
• Appendix 2. Human blood concentrations of major hormones
• Appendix 3. Clinically relevant endocrine disorders
• Appendix 4. The genetic code
• Appendix 5. Amino acid abbreviations
• Appendix 6. Units of measurement in biological systems
• Index

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