Hormones

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Autor: Gerald Litwack

ISBN: 9780323902625

Editura: Academic Press

Anul publicarii: 2022

Ediția: 4

Pagini: 474

Categoria: BIOCHEMISTRY

DESCRIERE

Hormones, Fourth Edition provides a report on the field of human hormones viewed in light of our current understanding of cellular and subcellular architecture, along with the molecular details of their modes of action. Comprehensive information about hormone action on canonical and non-canonical signaling pathways at cellular and subcellular level and effects on architecture and function of organ systems are discussed. All chapters in this new edition have been completely updated to cover advances in endocrinology research, which has expanded significantly in the last few years. Vast coverage of hormones not previously covered and newly discovered aspects of hormone action are also included. This new fourth edition is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for health professionals, clinicians and researchers in the field of endocrinology, metabolism and biochemistry.

Includes updates on all chapters
Covers sleep hormones, growth factors, intestinal hormones, calcium-sensing receptor of parathyroid, and others
Provides essential basics for advanced undergraduates, graduate students and researchers in the biological sciences, as well as clinical aspects and applications for clinicians
Presented in separate hormone systems, covering the subcellular mode of action of selected hormones and a detailed understanding of their human anatomy and physiology

Cover image
Title page
Table of Contents
Copyright
Dedication
About the author
Preface to the fourth edition
Chapter 1. Hormones: an introduction
Abstract
I Overview of hormones
II Hormone receptors
III Mechanisms of hormone action
IV Clinical aspects
Further reading
Chapter 2. Steroid hormones: chemistry, biosynthesis, and metabolism
Abstract
I Introduction
II Chemistry of steroids
III Biosynthesis of steroids
IV Serum-binding proteins for steroid hormones
Further reading
Chapter 3. The hypothalamus and anterior pituitary
Abstract
I Introduction
II Anatomical relationships
III Structure, synthesis, secretion, and target cells of the hypothalamic releasing hormones
IV Chemistry of the anterior pituitary hormones
V Regulation and biological actions of growth hormone and prolactin
VI The hypothalamus and appetite regulation
VII Clinical aspects
Further reading
Chapter 4. Posterior pituitary hormones
Abstract
I Introduction
II Anatomy of the posterior pituitary
III Chemistry, biosynthesis, and secretion of the posterior pituitary hormones
IV Biological actions of AVP
V Biological actions of oxytocin
VI Clinical aspects
Further reading
Chapter 5. Thyroid hormones
Abstract
I Introduction
II Anatomy of the thyroid gland
III Chemistry of the thyroid hormones
IV Synthesis and secretion of thyroid hormones
V Regulation of thyroid hormone secretion
VI Biological actions of T3
VII Clinical aspects
Further reading
Chapter 6. Pancreatic hormones: insulin and glucagon
Abstract
I Introduction
II Anatomical, morphological, and physiological relationships
III Chemistry, biochemistry, and biological activities of the pancreatic hormones
IV Clinical aspects
Further reading
Chapter 7. Gastrointestinal hormones
Abstract
I Introduction
II Anatomical and physiological relationships
III Biochemical properties and molecular actions
IV Clinical aspects
Further reading
Chapter 8. Eicosanoids
Abstract
I Introduction
II Structure and nomenclature of eicosanoids
III Synthesis and inactivation of eicosanoids
IV Eicosanoid receptors and signaling
V Examples of biological actions of prostaglandins
VI Clinical aspects
Further reading
Chapter 9. Calcium-regulating hormones: vitamin D, parathyroid hormone, calcitonin, and fibroblast growth factor 23
Abstract
I Introduction
II Anatomical and physiological relationships
III Chemistry and biochemistry
IV Biology and molecular actions
V Clinical aspects
Reference
Further reading
Chapter 10. Adrenal corticoids
Abstract
I Introduction
II Anatomy
III Biochemistry and biosynthesis of adrenal steroids and testosterone steroids
IV Biological and molecular actions of glucocorticoids
V Clinical aspects
Further reading
Chapter 11. Hormones of the adrenal medulla
Abstract
I Introduction
II Anatomical and physiological relationships
III Chemistry and biochemistry of the catecholamines
IV Biological actions of catecholamines
V Clinical aspects
Further reading
Chapter 12. Androgens
Abstract
I Introduction
II Anatomy of the male reproductive system
III Chemistry and metabolism of androgens
IV Regulation of androgen production
V Biological responses to androgens
VI Clinical aspects
Further reading
Chapter 13. Estrogens and progestins
Abstract
I Introduction
II Anatomy of the female reproductive system
III Chemistry and metabolism of female steroid hormones
IV Hypothalamic–pituitary–ovary axis
V Biological responses to female sex steroids
VI Clinical aspects
Further reading
Chapter 14. Hormones of pregnancy, parturition, and lactation
Abstract
I Introduction
II Anatomical relationships and the beginning of pregnancy
III Chemistry, biochemistry, and activity of the hormones of pregnancy
IV Parturition
V Lactation
VI Clinical aspects
Further reading
Chapter 15. Hormones related to the kidney and cardiovascular system
Abstract
I Introduction
II Anatomical, morphological, and physiological relationships
III Homeostasis of fluid, electrolytes, and blood pressure
IV Hormones and blood cell production
V Clinical aspects
Further reading
Chapter 16. The pineal gland
Abstract
I Introduction
II Anatomical features of the pineal gland
III Synthesis and secretion of melatonin
IV Biological actions of melatonin
V Clinical aspects
Further reading
Chapter 17. Growth factors
Abstract
I Introduction
II Epidermal growth factor
III Fibroblast growth factor family
IV Platelet-derived growth factors
V Insulin-like growth factors
VI Transforming growth factor β
VII Clinical aspects
Further reading
Appendix 1. Compilation of many known hormones in higher mammals and humans
Appendix 2. Human blood concentrations of major hormones
Appendix 3. Clinically relevant endocrine disorders
Appendix 4. The genetic code
Appendix 5. Amino acid abbreviations
Appendix 6. Units of measurement in biological systems
Index