Curcumin for Neurological and Psychiatric Disorders

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Autor: Tahira Farooqui Akhlaq A. Farooqui

ISBN: 9780128154618

Editura: Academic Press

Anul publicarii: 2019

Pagini: 350

Categoria: PSYCHIATRY

DESCRIERE

Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders.

The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium.

Key Features

Identifies molecular mechanisms of curcumin effects in neurological diseases
Includes effects on neurotraumatic, neurodegenerative and psychiatric diseases
Covers the antioxidant, anti-inflammatory and immunomodulatory effects of curcumin
Examines curcumin’s potential in developing new therapeutic drugs

1. Neurological and neuropsychiatric disorders
2. Curcumin: Historical background, chemistry, pharmacological action and potential therapeutic value
3. Curcumin in neurological disorders
4. Curcumin in neurological disorders: An overview
5. The potential role of curcumin in treatment and prevention for neurological disorders
6. The chemistry and biological activities of curcuminoids: Impacts on neurological disorders
7. Pharmacological effects of curcuminoids in neurological disorders
8. Anti-oxidant properties of curcumin: Impact on neurological disorders
9. Omics and epigenetics of polyphenol mediated neuroprotection: The curcumin perspective
10. Curcumin offers potential efficacy for treating Alzheimer’s disease
11. Potential role of curcumin and its derivatives against Alzheimer Disease
12. Usefulness of curcumin analogs for the diagnosis and treatment of Alzheimer Disease
13. Potential therapeutic impacts of curcumin against age-related impaired cognition and memory
14. Potential therapeutic impacts of curcumin for improving memory impairment
15. Curcumin derivatives as metal-chelating agents: Implications for potential therapeutic agent for neurological disorders
16. Neuroprotective propensity of Curcumin: evidences in animal models; Mechanisms and its potential therapeutic value
17. Molecular mechanisms of action of curcumin and its relevance to some clinical conditions
18. Therapeutic potentials of curcumin in Parkinson’s disease
19. Beneficial role of curcumin in preventing the aggregation of the Amyloid-β peptide in Alzheimer disease
20. Curcumin impact on multiple sclerosis
21. Potential therapeutic impacts of curcumin in treating epilepsy
22. The potential beneficial effects of curcumin in diabetic retinopathy
23. Current and combinative curcumin therapeutics for treating spinal cord injury
24. Curcumin and inflammatory brain diseases
25. Curcumin in depressive disorders
26. Summary, perspective and direction for future research