Crystal-Induced Arthropathies: Gout, Pseudogout and Apatite-Associated Syndromes

# With chapters by 35 respected experts on the topic, this sourcereviews clinical approaches to patients with crystal-induced arthritis, including information on pharmacologic interventions, complete with medications and dosing schedules
# covers the pharmacology of the most commonly used drugs and reviews mechanisms of action, side effects, drug interactions, indications, and contraindications for colchicine, nonsteroidal anti-inflammatory drugs, corticosteroids, xanthine oxidase inhibitors (including the newest one, febuxostat), and uricosuric agents
# analyzes potential new therapies such as parenteral uricase for the treatment of select individuals with gout and strategies to counteract the biologic effects of calcium containing crystals
# examines rare presentations of disease such as early onset gout, gout in women, and gout in organ transplant patients, as well as associated conditions such as cardiovascular and metabolic disorders
# summarizes classic radiographic research on the various forms of crystal-induced arthropathy and includes 26 radiographs that demonstrate these findings
# considers methods of crystal identification such as electron microscopy, atomic force microscopy, and Fourier transform infrared spectroscopy, and considers the applicability, cost, performance, sensitivity, and advantages of each technique


Divided into five expansive sections, this guide provides an in-depth review of crystal-induced arthritis and related disorders. Providing a historical perspective throughout, this work includes detailed descriptions of the clinical features of these diseases, as well as a current overview of their identification, epidemiology, genetics, and underlying pathophysiology. This authoritative guide also reviews case studies, current diagnostic tools, and the prevalence of these conditions while introducing new and emerging therapies for disease management.

REVIEW-URI