CLINICAL VIROLOGY

The essential reference of clinical virology

Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses.

Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections:

• Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections.
• Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. 

Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.

• Chapter 1: Introduction (Douglas D. Richman, Richard J. Whitley, Frederick G. Hayden)
• Section I: Viral Syndromes and General Principles
• Chapter 2: Respiratory Infections (John J. Treanor)
• Chapter 3: Viral Infections of the Central Nervous System(Kevin A. Cassady and Richard J. Whitley)
• Chapter 4: Gastrointestinal Syndromes (Eyal Leshem and Umesh Parashar)
• Chapter 5: Viral Hepatitis (Zina S. Valaydon, Steven A. Locarnini, Alexander J. V. Thompson)
• Chapter 6: Infections in Organ Transplant Recipients (John A. Zaia)
• Chapter 7: Viral Heart Disease (Bruce McManus, Michael Seidman, Karin Klingel, Honglin Luo)
• Chapter 8: Viral Infections of the Skin (Stephen K. Tyring and Zeena Y. Nawas)
• Chapter 9: Viral Hemorrhagic Fevers (Daniel Bausch and Cathy Ellen Roth)
• Chapter 10: Viral Disease of the Eye (Howard Newman)
• Chapter 11: Antiretroviral Agents (Scott Hammer)
• Chapter 12: Antiherpesvirus Agents (Claire Gordon, Christine Kubin, Scott Hammer)
• Chapter 13: Anti-Hepatitis Virus Agents (Scott Hammer)
• Chapter 14: Anti-Respiratory Virus Agents (Scott Hammer)
• Chapter 15: Diagnosis of Viral Infections (Guy Boivin, Tony Mazzulli, Martin Petric)
• Chapter 16: Immune Responses to Viruses (Galit Alter and Hendrick Streeck)
• Chapter 17: Immunization against Viral Diseases (Barney Graham)
• Chapter 18: Chronic Fatigue and Postinfective Fatigue Syndromes (Andrew Lloyd)
• Section II: The Agents
• Part A: DNA Viruses
• Chapter 19: Poxviruses (Stuart N. Issacs and R. Mark Buller)
• Chapter 20: Herpes Simplex Viruses (Richard J. Whitley and Bernard Roizman)
• Chapter 21: Cercopithecine Herpesvirus 1 (B Virus) (Richard J. Whitley)
• Chapter 22: Varicella-Zoster Virus (Anne A. Gershon and Michael D. Gershon)
• Chapter 23: Cytomegalovirus (Paul David Griffiths and Matthew Reeves)
• Chapter 24: Human Herpesvirus 6 and Human Herpesvirus 7 (Koichi Yamanishi and Yasuko Mori)
• Chapter 25: Epstein-Barr Virus (Joyce Fingeroth)
• Chapter 26: Kaposi's Sarcoma-Associated Herpevirus (KSHV/HHV8) (Yuan Chang, Shou-Jiang Gao, Patrick Moore)
• Chapter 27: Adenoviruses (Olli Ruuskanen, Jordan P. Metcalf, Matti Waris, Göran Akusjärvi)
• Chapter 28: Polyomaviruses (John Greenlee and Hans H. Hirsch)
• Chapter 29: Papillomavirus (William Bonnez)
• Chapter 30: Human Parvoviruses (Maria Söderlund-Venermo, Kevin Brown, Dean Erdman)
• Chapter 31: Anelloviridae (Peter Simmonds and Colin P. Sharp)
• Chapter 32: Hepatitis B Virus (Darren J. Wong, Steven A. Locarnini, Alexander J. V. Thompson)
• Part B: RNA Viruses
• Chapter 33: Human Lymphotropic Viruses: HTLV-1 and HTLV-2 (Roberta L. Bruhn, Renaud Mahieux, Edward Murphy)
• Chapter 34: Human Immunodeficiency Virus (John C. Guatelli, Robert F. Siliciano, Daniel R. Kuritzkes, Douglas D. Richman)
• Chapter 35: Colorado Tick Fever Virus and Other Arthropod-Borne Reoviridae (Steven Yukl and Joseph K. Wong)
• Chapter 36: Rotaviruses (Manuel A. Franco, Juana Angel, Harry B. Greenberg)
• Chapter 37: Respiratory Syncytial Virus, Human Metapneumovirus, and Parainfluenza Viruses (John V. Williams, Pedro Piedra, Janet Englund)
• Chapter 38: Measles (William J. Moss and Diane E. Griffin)
• Chapter 39: Mumps Virus (John W. Gnann)
• Chapter 40: Zoonotic Paramyxoviruses (Danielle E. Anderson and Lin-fa Wang)
• Chapter 41: Rhabdoviruses (Alan C. Jackson)
• Chapter 42: Filoviruses (Mike Bray and Daniel S. Chertow)
• Chapter 43: Influenza Virus (Frederick G. Hayden and Peter Palese)
• Chapter 44: Bunyaviridae: Orthobunyaviruses, Phleboviruses, Nairoviruses, and Hantaviruses (Greg J. Mertz, Clas Ahlm, Colleen B. Jonsson)
• Chapter 45: Arenaviruses (Daniel Bausch)
• Chapter 46: Enteroviruses (José R. Romero)
• Chapter 47: Rhinovirus (James E. Gern and Wai-Ming Lee)
• Chapter 48: Hepatitis A Virus (Sara E. Williford and Stanley Lemon)
• Chapter 49: Human Caliciviruses (Mary K. Estes and Robert Legare Atmar)
• Chapter 50: Hepatitis E Virus (David Anderson and Iswar Lal Shrestha) 
• Chapter 51: Astrovirus (Carlos F. Arias and Tomás D. López)
• Chapter 52: Coronaviruses (J. S. M. Peiris)
• Chapter 53: Arthropod-Borne Flaviviruses (Lyle Petersen and Alan D. T. Barrett)
• Chapter 54: Hepatitis C Virus (Christopher Koh, Qisheng Li, Jake Liang)
• Chapter 55: Alphaviruses (David Smith, John Mackenzie, Scott Weaver) 
• Chapter 56: Rubella Virus (David W. Kimberlin)
• Chapter 57: Infections Caused by Bornaviruses (Ralf Dürrwald, Norbert Nowotny, Martin Beer, Jens H. Kuhns)
• Part C: Subviral Agents
• Chapter 58: Hepatitis D (Mario Rizzetto, Antonina Smedile, and Alessia Ciancio)
• Chapter 59: Transmissible Spongiform Encephalopathies (Christina Sigurdson)