Biochemical and Molecular Basis of Pediatric Disease

Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases.

• Provides a fully-updated resource with more color illustrations
• Focuses on the biochemical and molecular basis of disease as well as the analytical techniques
• Defines important differences in the pathophysiology of diseases, comparing childhood with adult

Table of Contents

Dedication
Dennis J. Dietzen, Edward C. Wong, Michael J. Bennett and Shannon Haymond
Foreword
Preface
Dennis J. Dietzen
1. Pediatric Clinical Biochemistry: Why Is It Different?
Patricia M. Jones and Khushbu Patel
2. Current Approaches to Genetic Testing In Pediatric Disease
Jorge Granadillo and Khadija Belhassan
3. Data Analytics in Pediatric Laboratory Medicine
Stephen R. Master and Emily Gill
4. Disorders in the Neonatal Period
Edward C. Wong and Mary Revenis
5. Repiratory Disorders in the Neonate
Jeffery Dawson and Akshaya Vachharajani
6. Cardiac Disorders
Janetta Bryksin
7. Kidney and Urinary Tract Disorders
Rasheda Amin, Sun-Young Ahn and Asha Moudgil
8. Hepatic and Gastrointestinal Disorders
Stephen Matthew Roper, Janis Stoll and Sakil Kulkarni
9. Adrenal Disorders
Gabriela P. Finkielstain, Smita Jha and Deborah Merke
10. Biochemical and Molecular Evaluation of Thyroid Gland Disorders in Children
Edgard Delvin, Fabien Magne and Guy Van Vliet
11. Disorders of Growth
William E. Winter and Paul Hiers
12. Disorders of Calcium and Phosphate Metabolism in Infants and Children
Van Leung-Pineda and Maryam Salehi
13. Endocrine Emergencies
Jill D. Jacobson
14. Biochemical Genetic Disorders
Michael J. Bennett and Andrew Edmondson
15. Disorders of Iron Metabolism
Yaser Diab and Dennis J. Dietzen
16. Disorders of Porphyrin Metabolism
Silvia Tortorelli and Kimiyo M. Raymond
17. Erythrocyte Disorders
Emily Riehm Meier and Courtney Lawrence
18. Pediatric Bleeding Disorders
Yaser Diab, Michael F. Guerrera, Carrie Diamond and Julie Weisman
19. Pediatric Thrombotic Disorders
Edward C. Wong
20. Biological and Molecular Markers in the Diagnosis of Childhood Malignancies
Scott Raskin and Anne L. Angiolillo
21. Primary Immunodeficiency Diseases
Blachy Javier Dávila Saldaña, Michael Keller and Michael Edzards
22. Allergic Disorders
Alyssa James, Amaziah Coleman, Hemant P. Sharma and Wendy Paul
23. Autoimmune Disorders
Lawrence Jung and Wendy Paul
24. Cystic Fibrosis
Thomas W. Ferkol and Ferdinand Coste
25. Pediatric Therapeutic Drug Monitoring, Toxicology and Pharmacogenomics
Uttam Garg
26. Adolescent Disorders
Sarah K. Garwood and Mary Fournier
27. Pediatric Reproductive Disorders
Jami Josefson and Shannon Haymond
28. Disorders of Lipid and Lipoprotiein Metabolism
Alan Remaley and Rami A. Ballout
29. Neurological Disorders
Carlos Castillo Pinto and Marc T. DiSabella
30. Psychiatric Disorders
Finza Latif, Julie Berga

REVIEW-URI