Applications of Mass Spectrometry in Life Safety

This book brings into focus the hot topics of life science for which mass spectrometry is becoming. The tool of analysis, and provides a comprehensive review of the research topics most pertinent to the advancement of mass spectrometry and its general applications. The volume gathers the contributions from eminent international researchers in the field, covering various aspects ranging from the fundamentals of MALDI and ESI to their applications to most actual omics (proteomics, lipidomics, glycomics) or to immunology.The large group of small molecules analyzed with mass spectrometry technique is also represented by brominates and keratins, or plant extracts. It is hoped that this volume will also add stimulus for further progress in the field, where major challenges still remain and great potential exists for new breakthroughs. The ability of mass spectrometry for becoming a sound diagnosis technique of neurodegenerative diseases like Alzheimer, and for being a useful tool in immunotherapy is a fertile ground for further innovation and exploitation in the future.
Contents

Preface. I. Proteomics And Peptidomics.Blue Native PAGE and mass spectrometry analysis of ephrin stimulation-dependent protein-protein interactions in NG1O8-EphB2 cells
C.C. Dane et al.- Structure, Processing, and Polymerization of Rainbow Trout Egg Vitelline Envelope Proteins
C.C. Dane et al.- MALDI/MS Comparison of Fe-NTA Immobilized Metal Affinity Chromatography and Commercially-Available Metal Oxide Affinity Resins for Phosphopeptide Enrichment
M.B. Gates et al.- Molecular recognition specificity of anti-3-nitrotyrosine antibodies revealed by affinity-mass spectrometry and immunoanalytical methods
B.A. Petre et al.- II. Lipidomics.Mapping and sequencing of gangliosides from anencephaly by electrospray ionization high capacity ion trap mass spectrometry
C. Mosoarca et al.- III. Glycomics.Structural analysis of chondroitin sulfate disaccharides by electrospray ionization high capacity ion trap mass spectrometry
A. Muresan et al.- Application of high performance mass spectrometry to structural analysis of glycosaminoglycan oligosaccharides
D.G. Seidler.- Site specific identification of N-linked glycosylation in proteins by liquid chromatography -- electrospray ionization tandem mass spectrometry
I. Perdivara et al.- IV. Immunology.Characterization of lmmune Responses to Pathogen Challenge by MS Based Epitope Mapping
J.G. Williams et al.- Chemical Surface Modification and Chemical Crosslinking Combined with Mass Spectrometry for Protein Tertiary Structural Information
L.J. Deterding and K.B. Tomer.- V. Small Molecules.Brominated Flame Retardants: Analytical, Toxicological and Environmental Aspects
A. Covaci and A.C. Dirtu.- Stereochemistry studies of some 1,3-dioxane derivatives by differential mass spectrometry and computational chemistry
F. Harja et al.- MALDI-TOF Mass Spectrometry in Textile Industry
F.-D. Munteanu et al.- MALDI MS in Analysis of Keratin Fibre Proteins
A. Korner.- Chemical structure identification by differential mass spectra
N. Dinca.- List of Contributors.

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