Antifungal Therapy

This new edition of Antifungal Therapy aims at providing concise, practical, need-to-know information for busy physicians dealing with fungal infections, such as infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. It provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment including the basics of clinical mycology, management insights for various infections, evidence-based treatment recommendations, and helpful tables summarizing currently available pharmacokinetics data.

Key Features

• Features useful information on administration, dosage and pharmacology of antifungal drugs that can be difficult to use in clinical practice

• Contains common Clinical Questions & Answers to highlight frequently encountered patient issues

• Covers clinical mycology essentials in addition to antifungal treatment to create a well-rounded reference

• Presents illustrations and clinical photos in full color to elucidate the concepts

• Provides detailed evidence of treatment recommendations

Table of Contents

1. History of Antifungals

Kim Swindell and Emily Larkin

2. Epidemiology of Fungal Infections: What, Where, and When

Sylvia F. Costa, Fredric Lamoth and Barbara D. Alexander

3. Experimental Animal Models of Invasive Fungal Infections

Lisa Long and Chris Hager

4. Antifungal Drug Resistance: Significance and Mechanisms

Pranab K. Mukherjee, Sharvari Dharmaiah and Rania A. Sherif

5. Antifungal Prophylaxis: An Ounce of Prevention is Worth a Pound of Cure

Aimee K. Zaas

6. Preemptive Antifungal Therapy: do diagnostics help?

Kimberly E. Hanson, Vidya Jagadeesan

7. The immune response to fungal challenge

Jeffery Hu and Jeffery Aluetta

8. Immunomodulators: What is the evidence for use in mycoses?

J. Andrew Alspaugh

9. Fungal Biofilms and Catheter-Associated Infections

Jyotsna Chandra and Mahmoud Ghannoum

10. Polyenes for Prevention and Treatment Invasive Fungal Infections

Richard H. Drew

11. Flucytosine

Richard H. Drew

12. Pharmacology of Azole Antifungal Agents

Elizabeth S. Dodds Ashley

13. Echinocandins for Prevention and Treatment of Invasive Fungal Infections

Melissa D. Johnson, John Mohr and Ahmad Mourad

14. Novel Methods of Antifungal Administration

Richard H. Drew

15. Dermatophytosis

Nancy Isham and Mahmoud Ghannoum

16. Invasive Candidiasis

Rick Watkins and Tracy Lemonovich

17. Invasive Aspergillosis

Fran Esper

18. Management of Cryptococcosis

John R. Perfect and Ahmad Mourad

19. Management of Endemic Mycoses

John R. Perfect and Ahmad Mourad

20. Human Hyalohyphomycoses: A Review of Human Infections Due to Acremonium spp., Paecilomyces spp., Penicillium spp., Talaromyces spp. and Scopulariopsis spp.

Nour Hasan

21. Management of Phaeohyphomycosis

John R. Perfect and Ahmad Mourad

22. Pneumocystis

Kim Swindell

23. Management of Mucormycoses

John R. Perfect and Ahmad Mourad

24. Antifungal Management in Risk Groups: Solid Organ Transplant Recipients

Jasmine Chung, Sylvia F. Costa and Barbara D. Alexander

25. Prophylaxis and Treatment of Invasive Fungal Infections in Neutropenic Cancer and Hematopoietic Cell Transplant Patients

Hillard Lazaras, Marcie L. Riches and Daniel R. Richardson

26. Antifungal Use in Transplant Recipients: Selection, Administration and Monitoring

Richard H. Drew

27. Infants: Yeasts are Beasts in Early Life

Daniel Benjamin Jr. and Rachel Greenberg

28. Newer Antifungal Agents in PediatricsNewer Antifungal Agents in Pediatrics

William J. Steinbach

29. Fungal Infections in Burn Patients

Nour Hasan

30. Allergic Bronchopulmonary Aspergillosis

Nour Hasan

31. Fungal Infections of the Genitourinary Tract

Raymond Rackley and Cristina Rackley

32. Mycobiome in Health and Disease

Najla El-Jurdi, Pranab Mukerjee and M Ghannoum